Director, Modelling and Simulation

Director, Modelling and Simulation

Quotient Sciences

Nottingham, United Kingdom

Reporting to the VP, Scientific Consulting you will provide leadership for the Modelling and Simulation (M&S) team, managing resources to deliver customer projects meeting time, budget and quality criteria.

You will also drive customer adoption of M&S activities at Quotient, working with the commercial team to promote our scientific capabilities and secure new standalone and integrated programs of work. Assessing and adopting new M&S applications to increase the breadth of our offering to drive growth. Performing hands-on modelling and simulation (M&S) scientific support and input throughout the project lifecycle (design, planning, delivery and reporting) to ensure client’s study objectives are achieved

Main tasks and responsibilities:

  • Manage M&S team, ensuring availability of sufficient resources and capabilities for delivery of project work to agreed timelines and budget;
  • Prioritise activities to achieve agreed annual M&S order and revenue targets;
  • Work with the commercial and marketing team to promote Quotient’s M&S service offerings in the marketplace via appropriate channels and materials, including website, factsheet, scientific publications and conference attendance;
  • Provide scientific support to effectively communicate Quotient’s M&S capabilities and offerings in customer discussions;
  • Perform hands-on PBPK M&S activities to deliver customer projects;
  • Produce high quality reports which clearly present and summarise M&S project findings.

The Candidate:

The successful applicant will be degree qualified, ideally with a PhD with significant practice experience in building and applying physiologically based pharmacokinetic (PBPK) models across a range of applications, ideally utilising GastroPlus.

Significant experience in biopharmaceutics, PK data analysis and modelling, metabolism and clinical pharmacology with an ability to relate a compound’s in vitro physchem/biopharm/DMPK properties to preclinical and clinical in vivo performance.

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