Director of Medicinal Chemistry

Astex Pharmaceuticals

Cambridge, United Kingdom

The Role

Astex is seeking to appoint an experienced and influential medicinal chemistry leader; passionate about working on FBDD in close collaboration with scientists across computational chemistry, structural biology, drug discovery translational bioscience, and DMPK. The role requires high scientific rigour, and a desire to challenge and stimulate colleagues through scientific discussion. They will also have extensive medicinal chemistry experience, including lead optimisation, DMPK problem solving, a strong scientific reputation, including an outstanding publication history, a track record of leading drug discovery project teams and delivering high quality compounds to clinical trials. Experience with neuroscience and/or transmembrane targets would be desirable.

The director of medicinal chemistry will provide medicinal chemistry leadership on Astex portfolio projects, from target validation through fragments-to-leads, and lead optimisation stages, with an emphasis on structure-based drug design and state-of-the-art synthesis methodology. They will also contribute to the evolution of the chemistry department’s technology development and long-term strategy, apply innovative approaches to problem-solving and promote cross disciplinary interactions.

Skills and Experience

Ph.D. in chemistry with extensive experience in the drug discovery field.
Strong track record of scientific innovation in medicinal chemistry.
Recognised as an intellectual leader in drug discovery with a strong portfolio of patents, publications, and project achievements.
Demonstrated ability to plan and achieve research goals as part of an interdisciplinary team.
Experience of leading drug discovery project teams, identifying clinical candidates, managing scientific collaborations, and CRO outsourcing activities.

Apply Now

Don't forget to mention EuroPharmaJobs when applying.

Share this Job