Scientist Protein Engineering and Structural Bioinformatics - R&D Center - Spain

Almirall

Scientist Protein Engineering and Structural Bioinformatics - R&D Center - Spain

Almirall

Barcelona, Spain

Mission

The Almirall Research team in Barcelona is building up the biologics department and is looking for a talented protein Engineer/Structural Bioinformatician with expertise in computational protein and antibody modeling, engineering and design. He/she will provide computational support to advance Almirall’s biologics drug discovery programs on therapeutic monoclonal and multispecific antibodies.

Tasks and Responsibilities

Key responsibilities include but are not limited to:

  • Structure based design of high affinity antibodies;
  • Apply sequence analysis and structure modeling to epitope-paratope mapping and elucidation of mode of action;
  • Immunogenicity prediction, humanisation, affinity maturation and cross-reactivity engineering;
  • Use of predictive models to guide the design of optimal biophysical properties and developability potential;
  • Interact with internal and external experts, academic groups and CROs to establish, manage and follow-up projects and collaborations;
  • Project work in a highly collaborative and cross-functional environment;
  • Presentation at internal project, department and board meetings.

Education

  • PhD. in structural biology, computational biology or related field.

Experience

  • Experience in antibody modeling and engineering (preferentially in an industrial environment);
  • Experience in structure-based protein design software;
  • Experience in computer programming or scripting;
  • Experience in multi-specific antibody and non-antibody modalities is a plus;
  • Capacity to work in multiple projects in different therapeutic targets with clear understanding of project needs and ensuring delivery of high-quality data with clear communication of timeline;
  • Strong communication and team work skills.

Values and competencies

  • Caring: We always put our patient at the center. We listen and empathize. We help each other to succeed;
  • Dedicated: We are committed and passionate. We are bold and accountable. We never give up;
  • Dynamic: We are agile and keep things simple. We empower entrepreneurial mindsets. We challenge the status quo;
  • Expert: We dare to try and learn. We are rigorous in everything we do. We strive to always be one step ahead.

Apply Now

Don't forget to mention EuroPharmaJobs when applying.

Share this Job

© EuroJobsites 2020

EuroJobsites is a registered company number: 4694396 VAT number: GB 880 9055 04

Registered address: EuroJobsites Ltd, Unit 8, Kingsmill Business Park, Kingston Upon Thames, London, KT1 3GZ, United Kingdom

Newsletter | Recruit | Advertise | Privacy | Contact Us

© EuroJobsites 2020

EuroJobsites is a registered company number: 4694396 VAT number: GB 880 9055 04

Registered address: EuroJobsites Ltd, Unit 8, Kingsmill Business Park, Kingston Upon Thames, London, KT1 3GZ, United Kingdom

This website uses cookies to make your experience better. Continued use of this website means you accept our cookie policy.  Accept Cookies