Principal Scientist, Process Engineering

Principal Scientist, Process Engineering

BMS - Bristol-Myers Squibb

Moreton, United Kingdom

At Bristol Myers Squibb, we're looking for a Process Engineer to join our Chemical Process Development (CPD) team in Moreton, UK. CPD delivers clinical supplies and process development for all synthetic and anti-body drug conjugate (ADC) drug substances at BMS. This is a role where your engineering depth and your interpersonal skills will directly shape how - and how quickly - our clinical work reaches the patients who need them.

So, what does the role actually look like day-to-day?

You'll sit at the dynamic intersection between our internal science teams and the external Contract Development and Manufacturing Organisations (CDMOs) who bring our processes to life at scale.

On any given week, you might be:

• Reviewing a batch record for a hazardous chemistry campaign, making sure everything from safety and quality controls to process intent is technically accurate and operationally feasible before it goes near a plant;
• Walking a CDMO facility, either virtually or in person, assessing whether their equipment and capabilities are the right fit and if not, articulating exactly why and what needs to change;
• Troubleshooting a manufacturing issue, drawing on your engineering fundamentals and collaboration skillset to find the root cause and get things back on track;
• Presenting risk assessments and recommendations to leadership, translating complex technical realities into clear, actionable decisions;
• Building strong relationships with CDMO partners across the world – to improve how we work together and so that when things get difficult (and sometimes they will), you already have the trust in the room.

Is this you?

• You'll bring a B.Eng. or M.Eng. in Chemical Engineering and at least 10–15 years of industrial manufacturing experience - ideally in pharmaceutical drug substance manufacturing and GMP environments. Experience in specialty chemical or petrochemical industries is also acceptable;
• You know how to read a lab protocol and visualise how it will operate in a manufacturing environment;
• You can spot scale-up risk before it becomes a manufacturing incident;
• You have a strong grounding in chemical engineering fundamentals across reaction, crystallisation, distillation, extraction, filtration, drying, and milling;
• But just as importantly: you communicate clearly, you adapt your approach to the audience and the stakes, and you're comfortable managing complexity across multiple workstreams and stakeholders at once;
• Experience in lab-based small molecule development? Useful, but not essential.