Principal Scientist I - Novel Therapeutics

Principal Scientist I - Novel Therapeutics

AbbVie

Oxford, United Kingdom

Job Description

Successful applicant's key responsibilities

• Where appropriate act as molecule lead on pipeline programmes, providing technical expertise and cross-functional leadership as teams form around assets;
• Together with the team leader develop and deliver drug discovery strategy in alignment with AbbVie’s overall immunology strategy;
• Serve as a key lab focused scientist at the DJS-AbbVie Oxford site, and ultimately act as a recognised scientific expert within the wider AbbVie R&D organisation in your specialist mechanism of action;
• Collaborate with colleagues across immunology discovery research, development sciences, clinical development, and precision medicine;
• Ensure high-quality project planning through sound experimental design, early risk assessment and robust contingency planning;
• Identify and evaluate emerging scientific trends and translate relevant insights into functional objectives;
• Apply imagination and innovation to create and implement new or improved approaches and breakthrough ideas;
• Proactively share knowledge to build scientific capability within the team and foster a strong drug discovery mindset;
• Mentor junior colleagues and support their scientific development;
• Present scientific concepts and results to scientific and non-scientific audiences, including senior stakeholders and external partners.

Qualifications

Applicant’s essential attributes

• Demonstrated experience across multiple drug discovery programs with at least one proven example of a cell depletion modality;
• Education - BS, MS or PhD or equivalent experience in a relevant scientific area;
• Demonstrated ability to function as a principal investigator, generating original technical ideas and development strategies;
• Creative and practical problem-solving skills, with the ability to champion new technologies;
• Recognised as an expert in your discipline, internally and ideally externally;
• Strong publication, presentation, regulatory and/or patent record;
• Excellent scientific communication and presentation skills, including experience presenting at leading scientific conferences.

Applicant’s desired attributes

• Recognised expert in using cellular therapies e.g. CAR-T, CAR-NK, CAR-Treg, etc.;
• OR recognised expert in complex antibody engineering including bispecific and novel formats;
• Strong background in translational biology.