Associate Director, Pharmacology

Associate Director, Pharmacology

Grifols

Dublin, Ireland

POSITION SUMMARY

The Associate Director, Pharmacology will responsible for leading non‑clinical and early clinical pharmacology strategy across drug development programs. Provides expertise in PK/PD, modeling & simulation, and Model‑Informed Drug Development (MIDD) to support dose selection, study design, and regulatory submissions. Partners cross‑functionally with clinicians and statisticians, represents Pharmacology on global teams, and mentors junior scientists while ensuring scientific excellence and regulatory compliance.

What You Will Do

• Lead PK/PD data analysis and modeling activities, applying mechanistic and population modeling approaches using tools such as Phoenix WinNonlin, NONMEM, and related platforms.
• Apply quantitative and statistical methods to support non‑clinical and early‑phase clinical pharmacology programs.
• Contribute to regulatory interactions and submissions, including INDs, BLAs, MAAs, Investigator’s Brochures, briefing packages, and responses to agency queries.
• Communicate complex clinical pharmacology concepts clearly and effectively to cross‑functional and external stakeholders.
• Provide scientific leadership in matrixed teams, driving pharmacology strategy, problem‑solving, and decision‑making across programs.
• Lead the analysis, integration, and reporting of clinical pharmacology data to inform dose selection and study design.
• Design and implement pharmacology plans and ensure best practices across project teams.
• Partner with clinicians and statisticians to optimise dosing strategies and clinical study designs.
• Oversee study‑level pharmacology activities, including protocol and SAP development, execution, and reporting.
• Drive the design and execution of Model‑Informed Drug Development (MIDD) strategies.
• Represent Pharmacology on global program teams, clinical sub teams, and other multifunctional groups.
• Mentor and coach junior colleagues and team members.
• Stay current with scientific literature, regulatory guidelines, and internal SOPs.

What You’ll Bring

• A doctoral degree (PhD) or equivalent professional training (PharmD), or post‑doctoral experience in clinical pharmacology, pharmacokinetics, pharmacology, toxicology, pharmaceutics, or a related scientific discipline.
• A minimum of 3+ years of relevant industry or academic experience supporting pharmacokinetic, pharmacodynamic, and broader pharmacology activities across non‑clinical and early clinical drug development programs.
• Hands‑on experience contributing to pharmacology strategy and execution within pharmaceutical or biotechnology environments, with the ability to apply scientific rigor in a fast‑paced, collaborative setting.