Senior/Principal Scientist - Drug Metabolism & Biotransformation

Senior/Principal Scientist - Drug Metabolism & Biotransformation

Servier

Gif-sur-Yvette, France

We are seeking a highly experienced Senior or Principal Scientist to join our Biotransformation & Biodistribution Team within the Global DMPK Department. You will play a key role in designing, conducting, and reporting preclinical and clinical biotransformation studies, driving the successful development of drug candidates to patients.

Key Responsibilities

• Design and execute biotransformation studies to support drug development.
• Characterize metabolites using advanced analytical techniques (LC-HRMS/MS, LC-Rad).
• Collaborate with cross-functional teams (chemistry, pharmacology, toxicology, regulatory).
• Interpret and present results, ensuring scientific excellence.
• Mentor junior scientists and foster an innovative research culture.
• Contribute to publications, patents, and regulatory submissions.

Profile

• PhD in Biochemistry, Chemistry, Molecular Biology, Pharmacology, or related field.
• 10+ years of experience in drug metabolism/biotransformation.
• Proven track record in late discovery and development, including clinical samples.
• Expertise in enzymology, metabolic pathways, and advanced analytics.
• Experience with µdose/µtracer AMS studies is a plus.
• Strong leadership, problem-solving, and communication skills.