Scientist I, Bioreactor Process Development

Scientist I, Bioreactor Process Development

Evotec

Toulouse, France

What You’ll Do:

• Assisting in all Lab activities including experiment execution, Bioreactor assembly, Autoclave, Media/buffer preparation, Bioreactor sampling and daily sample analysis, Sample storage etc.
• Executing statistically designed experiments (DOE) either independently or with support from Senior Scientists/manager.
• Responsible for bench-scale bioreactor operations including run preparation, bioreactor assembly, autoclave, inoculation, daily sampling and analytics, troubleshooting, cleaning, and maintenance.
• Responsible for equipment calibrations and Media preparations in the Lab.
• Ensure accurate and complete documentation of lab activities and write appropriate technical reports for successful regulatory submission.
• Ensure the upstream development (USP) labs and equipment is maintained under optimal working conditions and assume responsibility for specific instruments.
• Contribute to investigations (e.g., deviations) as required to help identify the root cause and propose and implement appropriate corrective actions.
• Carry out Development/Characterisation/optimisation experiments, accurately document results, and produce experimental reports. Support tech transfer with manufacturing organizations (internal and external).
• Responsible for own professional attitude and for sharing knowledge for the benefit of others or on demand.
• Author, amend and review operating documents, such as WI, SOPs, guidelines, and data records. Willing to take on additional activities.
• Documenting best practices and technical results in ELNs, SOPs, summary reports, etc.
• Working with vendors and manufacturers.
• Potential for weekend work.

Your profile:

• Master’s degree in engineering, Biochemistry, Biotechnology or related field with 0 – up to 5 years of experience.
• Proficiency in both verbal and written English is essential.
• Excellent attention to detail, focused when completing technical tasks.
• Strong writing skills and efficient at documentation.
• Excellent experimental design and analysis skills.
• Able to stay organized in complex situations, keep track of multiple tasks and data.
• Enthusiastic problem-solver.
• Experience with Microsoft Office apps (Word, PowerPoint, Excel).
• Experience with cell culture operations, filtration techniques, automation, analysing data using statistical tools.

Pluses:

• Experience with aseptic technique and small-scale cell culture.
• Experience with upstream bioprocessing equipment, especially perfusion technology, as well as analytical or downstream purification equipment.
• Experience maintaining and troubleshooting scientific or electronic equipment.
• Experience preparing cell culture media and buffers.
• Experience with design of experiments (DOE) and statistical analysis.
• Experience with paper or electronic lab notebooks or other record-keeping methods.
• Experience analyzing data in tools such as JMP, R, or Python.
• General understanding of cell biology, fluid dynamics, and biotransport.
• General understanding of circuits (grounding, power, signal, etc.).
• Experience working in a cGMP or clean room setting (this job is non-GMP but knowledge of GMP is helpful for process/tech transfer activities).
• Experience working in retail, service industry, or other environments that require physical work and positive attitude.
• Experience in training, mentoring, and supervising team members.