Scientist, Advanced Bioassay & Characterization

Scientist, Advanced Bioassay & Characterization

Genmab

Utrecht, Netherlands

The role

We are seeking a Scientist, Advanced Bioassay & Characterization (ABC) to join our Analytical Development department, which is part of CMC Product Development. ABC plays a crucial role in ensuring the quality and characterization of Genmab’s antibody products by developing bioassays to demonstrate the quality and characteristics of our antibody products (to be) used in clinical studies.

As Scientist ABC, you will be working in a team of scientists and research associates dedicated to developing and validating functional bioassays. Specifically, you will design and develop bioassays for projects in the clinical development stage. You are expected to provide scientific support for decision making based on your knowledge of different traditional technologies as well as more advanced techniques like SPR. In addition, you will participate in cross-functional product characterization studies to support regulatory filing.

You recognize yourself as result driven, energized by delivering high quality results and having passion for technological advancements in the bioassay field. With your solid bioassay knowledge and excellent communication skills, you represent the CMC bioassay expertise within our organization. The position will report to the Associate Director, Head of Advanced Bioassay & Characterization.

Responsibilities

• Subject matter expert on cell-based potency assays, such as viability assays, reporter gene assays and primary cell-based assays.
• Scientific oversight of assay development and structure-function studies.
• Act as an author/reviewer of necessary documentation.
• Collaborating with internal and external stakeholders.
• Planning and prioritization of own work packages.
• Set high quality standards and take initiatives to improve ways of working and processes.
• Work in cross-functional teams to meet project deliverables.

Requirements

• A PhD in a relevant life science field or MSc with several years of relevant experience.
• Experience with developing and troubleshooting of cell-based assays (e.g. luminescence assays, flow cytometry, Incucyte), preferably within industry or in a regulated setting.
• Experience with statistics (JMP) and developing assays according to aQbD principles would be advantageous.
• Affinity for introducing automated solutions for assay development.
• Affinity for digitalization/AI and its application in assay development environment.
• Experience with developing SPR-based assay would be beneficial.
• Proven ability to run several projects parallel to each other and adjust priorities appropriately with the team.
• Ability to translate scientific theory into practical, compliant laboratory workflows and to interpret data in the context of bioassay development and product characterization deliverables.
• Excellent relational and communication skills in English. Previous experience of managing external collaborations is beneficial.
• Motivated by working in an inclusive and collaborative work environment.

About You

• You are genuinely passionate about our purpose
• You bring precision and excellence to all that you do
• You believe in our rooted-in-science approach to problem-solving
• You are a generous collaborator who can work in teams with a broad spectrum of backgrounds
• You take pride in enabling the best work of others on the team
• You can grapple with the unknown and be innovative
• You have experience working in a fast-growing, dynamic company (or a strong desire to)
• You work hard and are not afraid to have a little fun while you do so!