Clinical Trial Manager

Clinical Trial Manager

Ascendis Pharma

Hellerup, Denmark

We are seeking a passionate Clinical Trial Manager to join our growing team. As a key member of the Ascendis Pharma team, you will play a crucial role in driving the effective conduct of global clinical trials within our endocrine rare disease programs, ensuring timely delivery and high quality to help make a meaningful difference in patients’ lives. This is an exciting opportunity to work in a fast-paced environment, collaborate with cross-functional, global teams working together to achieve extraordinary results.

You will be joining the Clinical Operations team consisting of 10 colleagues, and report directly to Betina Steenberg, Director, Clinical Operationswho is based in Hellerup like you will be.

Your key responsibilities will be:

• Provide operational input to clinical trial protocols and support trial set-up, including development of key documents (e.g., consent forms, data collection tools, management plans).
• Manage and oversee CROs, vendors, and clinical trial sites, including participation in selection, qualification, initiation, and close-out activities.
• Monitor trial progress and site performance through metrics, recruitment tracking, co-monitoring visits, and site engagement efforts.
• Ensure quality and compliance through review of protocol deviations, safety data, and oversight/QC of the Trial Master File (TMF).
• Support regulatory and ethics submissions, investigator/monitor meetings, and contribute to clinical SOPs within the Ascendis Quality Management System.

Qualifications and Skills:

You hold a relevant academic degree – a bachelor’s or master’s degree in natural or health science (biology, pharmacology, pharmaceutical science or equivalent) – have minimum five years of experience in managing clinical trials. You have experience with day-to-day operational management and oversight of clinical trials. You are proficient in English at a professional level, both written and spoken.

Furthermore, you have:

• Project management mindset with a good understanding of the drug development process.
• Experience with all aspects of clinical trial conduct from planning and start-up, through maintenance and to closure.
• Thorough understanding of GCP and relevant regulatory guidelines and know how to apply it to your work.

Key competencies:

You have a strong can-do attitude.

You possess an entrepreneurial mindset and can thrive in an informal, open environment where innovation and change are key.

To succeed in this role, we also expect you to be:

• Structured, organized and a proactive problem-solver, striking the right balance between detail and progress.
• Team player who understands and appreciates how to build effective relationships with both internal and external stakeholders.
• Flexible and highly committed to delivering outstanding results.

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