Senior Scientist - Antibody Production

Senior Scientist - Antibody Production

UCB - Union Chimique Belge

Slough, United Kingdom

About the role

You will form part of a multi-disciplinary team generating antibody and antibody related proteins to support new drug candidate discovery and development. As a laboratory-based research scientist, you will be responsible for key aspects in the production, characterisation, logistics management and long-term storage of high-quality antibodies. You will therefore contribute to the progression of molecules from the earliest stages of drug discovery all the way to drug candidate.

What you’ll do

• Purify, analyse and share/store high-purity antibodies destined for use in pre-clinical projects and in supporting studies for later stage/clinical antibody projects.
• Liaise with project leads and antibody engineers to understand, capture and prioritise antibody reagent requests.
• Be the owner of and curate a purified antibody reagent database and liaise with colleagues requiring samples and information across Research and Early Clinical Development.
• Generate, analyse, interrogate, and document data using electronic lab notebooks and sample management/registration systems.
• Communicate data through project presentations and written reports, including more formal documentation when related to clinical phase projects or external collaborators and service providers.
• Innovate or identify and implement new and relevant technologies for capacity or technology expansion.

Interested? For this role we’re looking for the following education, experience and skills

• A BSc graduate with a demonstrable knowledge of and experience with proteins and antibodies (MSc/PhD or industrial experience in a relevant biological discipline may be advantageous).
• Experienced in purification techniques and use of purification platforms (e.g. Affinity chromatography, IEX, HIC, SEC, AKTA).
• Detailed, broad knowledge and experience of antibody purification methods: chromatography, resins, buffer condition and the impact of production scale.
• Practical experience with analytical assays for characterisation, purity and biophysical understanding of proteins/antibodies.

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