Scientist, Exploratory Biopharmaceutics

Scientist, Exploratory Biopharmaceutics

BMS - Bristol-Myers Squibb

Moreton, United Kingdom

Position Purpose

As a Scientist in Exploratory Biopharmaceutics (EB) of Drug Product Development (DPD) you can make a real impact on patient lives. You will collaborate with multi-disciplinary teams to develop novel, safe, and effective therapeutic molecules. We are seeking a dynamic individual with expertise in modeling/simulation, pharmaceutics, DMPK, ADME, and chemistry. You will thrive in our fast-paced, innovative environment, leveraging your organizational, communication, and critical thinking skills to deliver robust products.

Key Responsibilities

  • Develop biopharmaceutics strategies to pursue desired therapeutic exposure for active clinical and nonclinical studies;
  • Design and develop pharmacokinetic models to identify biopharmaceutics performance attributes that are critical for successful clinical progression;
  • Develop an integrated biopharmaceutics modeling and simulation package for regulatory interactions and dossier submissions;
  • Effectively manage development projects with minimal supervision;
  • Provide independent interactions with multiple functional groups including Discovery, Clinical Pharmacology, Regulatory, and Toxicology;
  • Know how to work in a collaborative Pharmaceutical Development environment across groups and therapeutic areas.

Required Education and Experience

  • Ph.D. and experience within commercial pharmaceuticals; or
  • MS and extensive experience within commercial pharmaceuticals.

Required Skills and Competences

  • A sound understanding of ADME, PK, and PK-PD principles and hands-on modeling experience. (e.g. PBPK, PD, popPK, QSP, etc.);
  • Knowledge of drug substance and drug product manufacturing processes;
  • Effective communication and collaboration skills to work within and lead cross-functional teams;
  • Demonstrated problem-solving skills and ability to work and collaborate in a multi-discipline team setting are must to this job function;
  • Detail-oriented with excellent organizational and documentation skills;
  • Ability to adapt to changing priorities and work in a fast-paced environment;
  • Demonstrated expertise through a record of publications and presentation and familiarity with state-of-the-art academia and industry applied biopharmaceutics, pharmacokinetics, and ADME principles;
  • Demonstrated passion for fostering innovation and working with an entrepreneurial mindset in a matrix environment.

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