Senior/Principal Translational Medicine & Biomarker Lead - Precision Medicine
Senior/Principal Translational Medicine & Biomarker Lead - Precision Medicine
Boehringer Ingelheim
Biberach, Germany
OUR COMPANY
At Boehringer Ingelheim we develop breakthrough therapies and innovative healthcare solutions in areas of unmet medical need for both humans and animals. As a family owned company, we focus on long-term performance. We believe that, if we have talented and ambitious people who are passionate about innovation, there is no limit to what we can achieve; after all, we started with just 28 people. Now, we are powered by 50,000 employees globally who nurture a diverse, collaborative and inclusive culture.
THE POSITION
Are you an expert in Precision Medicine, Biomarkers or Translational Medicine? Do you have extensive experience in Companion Diagnostic (CDx) as well as clinical drug development, and a deep knowledge of Oncology and other relevant disease areas? Boehringer Ingelheim is currently seeking a TMCP Precision Medicine Lead for the implementation of Precision Medicine/CDx concepts in drug development programs to be based in Biberach/Germany.
Translational Medicine & Clinical Pharmacology (TMCP) is a global organization within the Innovation Unit that builds understanding of diseases and drugs by developing and applying innovative translational strategies (including biomarkers, clinical pharmacology, pharmacometrics and digital approaches) across the entire clinical development pipeline. We drive projects fast and stringently to informed decisions on first-in-man, proof of pharmacological principle (PoPP), proof of clinical principle (PoCP) and proof of clinical concept (PoCC) up to submission. To generate an integrative understanding of the dose-exposure-biomarker-response/clinical end-point relationship and to maximize translational knowledge generation, we are applying state-of- the-art technologies and data analytics, support start of development (SoD) decision points and enable Precision Medicine to deliver differentiated therapies for patients.
Discover our Biberach site: xplorebiberach.com.
Tasks & responsibilities as Senior Translational Medicine & Biomarker Lead Precision Medicine
- As TMCP Precision Medicine Lead you will advise project teams on Precision Medicine/CDx strategies, e.g. regarding patient selection strategies, clinical trial design and identification & application of biomarkers predictive for drug response from a CDx perspective;
- In your role as leader of CDx Integration teams you will be accountable for the successful implementation of CDx in drug development programs to ensure timely submission of BI drug and associated CDx test in close collaboration with external CDx partners as well as with BI functions, e.g. TMCP Biomarker Platforms, Regulatory Affairs, Medicine;
- You will support clinical teams regarding CDx in BI-internal decision-making committees (e.g. CEC, TALC, HPSC) and in strategic discussions, including agency meetings;
- You will provide internal advice and support through BI´s CDx Center to enable decision making regarding appropriate CDx opportunities;
- You will represent BI in Joint Project teams between BI and external CDx partners;
- You will support qualification and management of third party laboratories and IVD partners, support CDx provider audits to ensure third party QC/QA and regulatory compliance;
- You will contribute to early and late stage CDx-related topics in in-licensing opportunities, incl. due diligence and deal execution;
- You will monitor the external CDx landscape for emerging opportunities, technologies and trends and changes in regulation/legislation.
As Principal Translational Medicine & Biomarker Lead Precision Medicine
- In the Principal role, you act as the primary internal reference contact concerning translational and biomarker approaches in Precision Medicine.
Requirements for a Senior-Position
- Medical degree or PhD in Life Sciences with a special focus on Precision Medicine/CDx;
- Appropriate scientific and individual qualification with several years of working experience in the development and implementation of biomarker/CDx concepts in a pharmaceutical or diagnostic company;
- Expert-level knowledge and experience in Precision Medicine, CDx and clinical drug development, as well as a clear understanding of the applicable regulatory requirements;
- Profound disease-area knowledge (in particular Oncology) with strong scientific knowledge of the pathophysiology and the main therapeutic modalities currently approved or in clinical development is advantageous;
- Personal track record in the implementation of biomarkers/CDx assays in drug development with an understanding of the clinical application of such markers, their evaluation and analysis, and the linkage between the biomarker and clinical endpoints;
- Evidence of strategic and creative thinking, a team-oriented attitude, solid negotiation skills and strong team-working competencies to collaborate successfully in a matrix environment;
- The ability to communicate effectively and in an integrative manner with internal and external experts and opinion leaders.
Additional requirements for a Principal Position
- Longer duration of experience in relevant clinical area with significant time spent directing translational medicine or biomarker research projects.
EFFECTS OF COVID-19
We will continue to hire talented people and we look forward to receiving your applications. As a result of COVID-19, we have introduced alternative working arrangements to ensure that our employees can stay safe and healthy, because the health of our employees is among our top priorities. At all company locations, we work remotely whenever possible. Additionally, we are now hosting virtual video interviews for applicants. During the limited in-person interviews we still have during this time, we pay special attention to distance and the hygiene rules recommended by the Robert Koch Institute. New employees who do not start on site in production or the laboratories are sent the necessary IT equipment, our Welcome Days take place online, and we plan to conduct their onboarding training virtually whenever possible.
WHY BOEHRINGER INGELHEIM?
This is where you can grow, collaborate, innovate and improve lives.
We offer challenging work in a respectful and friendly global working environment surrounded by a world of innovation driven mindsets and practices. In addition, learning and development for all employees is key, because your growth is our growth. We also offer a competitive salary, generous amount of vacation time, and numerous benefits towards your wellness & financial health and work-life balance. Plus, an onsite gym (Ingelheim), in-house doctor and best-in-class cafeterias and coffee bars to keep you energized and healthy. To learn more about what benefits could be waiting for you, please visit our Career area.
Want to learn more about us? Visit https://www.boehringer-ingelheim.com/.
Boehringer Ingelheim is an equal opportunity global employer who takes pride in maintaining a diverse and inclusive culture. We embrace diversity of perspectives and strive for an inclusive environment, which benefits our employees, patients and communities. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or national origin.
READY TO CONTACT US?
Please contact our Recruiting EMEA Team, Tel: +49 (0) 6132 77-173173.
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