Senior Principal Scientist - Process Development - Upstream

Senior Principal Scientist - Process Development - Upstream

Lonza

Slough, United Kingdom

In this role, you will be working as a Member of Process Development Sciences (PDS) – A focused group of senior subject matter experts (SMEs), with extensive experience in upstream and downstream science and in product characteristics, who provide scientific and technical solutions that support process development and MSAT teams throughout the global Lonza biomanufacturing network. PDS provides governance of the development process, troubleshooting consultancy and collaborating on assessment and introduction of innovative new technologies. As foremost expert in your field, you will be comfortable providing recommendations and guidance to customers, senior management and functional project teams.

This support is provided to all Lonza project teams and the customer themselves, across all sites in the Lonza mammalian network. To be successful in this role, you must have a broad width of experience in upstream cell culture development and manufacturing, be passionate about the science that underlies complex technical challenges, and effective at sharing knowledge that supports the development of talented scientists.

Key responsibilities:

  • Providing strong scientific support of processes for the development and manufacture of therapeutic proteins by mammalian cell culture. Have in depth knowledge across a range of USP. This may include, for example: pre-clinical and clinical process development, process transfer into cGMP, upstream processes, leading RCAs; leading risk assessments; DoE; multivariate analysis; FMEA; supporting regulatory inspections and interactions
  • Leading multi-disciplinary matrix teams to resolve issues (technical, scientific, IP, for example) through a structured data driven approach, such as Root Cause Analysis, which affect, or have the potential to affect, development and execution of mammalian cell culture processes for the manufacture of therapeutic proteins, within the Lonza network.
  • Provide governance oversight of the process from gene to IND and process characterisation to BLA.
  • Ensuring investigations deliver robust, documented reports to agreed timelines
  • Coaching and mentoring scientists in Process Development
  • Working with R&D and operations groups to ensure that innovative approaches or new technologies under development have a valuable beneficial impact to Lonza operations
  • Through knowledge of best practice, propose and lead the implementation of new processes that enhance the capability and effectiveness of Lonza operations.
  • Ensure a high standard of science and quality of work is maintained for customer and in-house projects
  • Recognise and disseminate information about emerging trends (scientific, technical, IP, etc) that impact Lonza’s ability to deliver its customers‘ projects or win business in both short and long terms
  • Able to communicate effectively including presentation to customers, peers, internal stakeholders and at conferences

Key requirements:

  • PhD or BSc + additional years’ experience in a relevant scientific discipline.
  • Strong previous experience in upstream bioprocessing working within an industrial environment.
  • Has the ability to recognise and disseminate information about emerging trends (scientific, technical, IP, etc) that impact Lonza’s ability to deliver its customers‘ projects or win business in both short and long terms.

Apply Now

Don't forget to mention EuroPharmaJobs when applying.

Share this Job

© EuroJobsites 2020

EuroJobsites is a registered company number: 4694396 VAT number: GB 880 9055 04

Registered address: EuroJobsites Ltd, Unit 8, Kingsmill Business Park, Kingston Upon Thames, London, KT1 3GZ, United Kingdom

Newsletter | Recruit | Advertise | Privacy | Contact Us

© EuroJobsites 2020

EuroJobsites is a registered company number: 4694396 VAT number: GB 880 9055 04

Registered address: EuroJobsites Ltd, Unit 8, Kingsmill Business Park, Kingston Upon Thames, London, KT1 3GZ, United Kingdom

This website uses cookies to make your experience better. Continued use of this website means you accept our cookie policy.  Accept Cookies